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RESEARCH ON NEUROGENESIS
Script and slides from the documentary:
“ORIGINAL HOME-VIDEO CLIPS SHOWING THE GENUINE PERSONAL EXPERIENCES OF PARKINSON’S DISEASE AND MSA SUFFERER’S.”
1.- Parkinson’s Disease
Video Filmed in January 2003
Patient ID Code: LG-1998
The first patient shown on this video is an 89 year old lady, diagnosed with Parkinson’s disease 4 years ago. A medical history, and report, with further details, is available for doctors interested in receiving additional information on this woman.
In 1999 she was diagnosed with Parkinson’s disease and prescribed the drug Sinemet 25/100. She tried it for a short time, soon after, this drug had to be discontinued due a bad reaction to it and to undesirable side effects.
In April 1999, she started our Neurogenic dietary intervention programme, which resolved efficiently her gait disturbance and did not cause her any side effects at all.
After one year of using the Neurogenic diet, she was able to walk independently without the aid of a cane. At the time of diagnosis, she suffered from a moderate bradykinesia. One year later, there was no apparent sign of a bradykinetic problem at all.
During the second year on the Neurogenic diet, she became totally independent in the morning. She was able to prepare breakfast, dress herself and go out for a walk without any assistance.
After four years on the Neurogenic diet, the disease did not show any progression. Instead, there was an apparent disappearance of many of the initial symptoms that lead to the diagnosis of Parkinson’s disease in 1999.
In December 2002, at her fourth year on the Neurogenic programme, the woman’s daughter filmed a tape for us and her doctor to show that her mother was now able to perform exercises which were impossible to do a year earlier.
This exercise consists of lying on the floor by herself and lifting herself up from the floor, without assistance. This demonstration was filmed at 10 am. The last time she had taken her extract was the previous day at 6 am, that is, 28 hours earlier.
The exercise that she had done, is a difficult exercise for anyone at the age of 89, but particularly for anybody suffering for Parkinson disease.
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2. - MULTIPLE SYSTEM ATROPHY. (MSA-P)
Video Filmed in December 2002
Patient ID Code: LB-1997
The second patient presented in this video documentary, was diagnosed, two years ago, as having Parkinson’s Disease. Two months ago, her neurologist realized that she had developed MSA-P. This is a Multiple System Atrophy of the Striatonigral Degeneration Type.
The patient was experiencing serious difficulties in breathing, walking, had a very poor balance, dryness of mouth, difficulties in swallowing, intermittent sleep, constipation, and several other symptoms that were making her life almost unbearable.
We asked her family to record a video tape for us, to allow us to have a better understanding of her condition and problems.
On the 15th of December 2002, she started on the first stage of our Neurogenic diet, which concentrates mainly on the replacement of any drugs that might be causing adverse reactions.
A few weeks later, as soon as the drugs Sinemet and Amantadine were reduced by 50%, most of the severe symptoms she was experiencing had decreased significantly.
The family continued to video tape her over the New Year holidays and, with great surprise, they realized that their mother was showing quick and very dramatic improvements.
This important visual testimony helps to demonstrate that, in some instances, the symptoms thought to be of a Parkinson’s disease condition progressing into an MSA condition, might not be the real scenario. Instead, the severity of the symptoms might originate due to an exacerbation of adverse reactions to drugs and chemicals to which the patient is highly sensitive.
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AREAS OF THE BRAIN AFFECTED IN MSA
A number of areas of the brain are affected by MSA. This has led to different varieties of MSA receiving different names, depending on which area of the brain has predominant involvement.
When a patient initially has rigidity (stiffness) and slowness in initiating movements (bradykinesia) which is out of proportion to tremour, this MSA form has been called striatonigral degeneration, involving communication between nerve cells in the striatum and midbrain. This is the form of MSA which has been diagnosed for this patient. It is also called MSA-P, because it resembles the symptoms of Parkinson’s disease.
With patients in whom changes in autonomic function dominate the initial presentation, particularly changes in blood pressure regulation, the MSA form is often called Shy-Drager syndrome.
When MSA begins with imbalance, incoordination, and difficulty in speaking (dysarthria), it is often called olivopontocerebellar atrophy; as the name suggests, this form of MSA is marked by degeneration in the cerebellum, a structure involved in balance and learned motor tasks.
3. - MULTIPLE SYSTEM ATROPHY. (MSA-C)
Video Filmed in Fed 2003
Patient’s Privacy ID Code: MW-2002
The following patient suffers from this type of MSA, which is also called also MSA-C because the areas affected involve the cerebellum.
Patients suffering from MSA-C usually do not show any response to the standard parkinsonian medication.
This is precisely the case of the fourth patient presented in this video. She did not show any response to Sinemet. Moreover, she was affected by serious side effects which are not usually present, in the first year, in most of the patients using this drug.
We would like to suggest that this patient, as many diagnosed today with MSA, might suffer from a high sensitivity to specific synthetic chemicals. This chemical sensitivity might be a confusing determinant when trying to diagnose the disease.
This patient showed rapid improvement, after using a purely organic dietary intervention. We can assume, therefore, that she suffers from a high sensitivity to non-organic chemicals.
This suggestion is endorsed by another experience. When this patient started on a clinical trial for a new drug for MSA, she had to drop out at the very beginning of the study, because of adverse reactions and innumerable side effects.
Most of the other patients in the trial, were not troubled by these side effects. The chemical sensitivity in this patient is higher than normal. For this particular type of patient, who cannot tolerate large doses of drugs, we need to consider prescribing organic interventions with natural products that can help them in a similar way as with the drugs, but without adverse reactions, that can sometimes confuse the diagnosis.
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4. - PARKINSON’S DISEASE
Video Filmed in Dec. 2002/ Jan 2003
Patient’s Privacy ID Code: PL-2002
The fourth patient, presented in this documentary, had been suffering from Parkinson’s disease for 20 years. She is now 78 years old. She is 11 years younger than the previous patient shown in this video.
She took Sinemet 25/100, four to six times a day, during the first 15 years she had the disease. During the period she was taking Sinemet, she had sensitive reactions against it, which made her suffer from a number of side effects, over many years.
She started on the Neurogenic diet in 1997, that is, almost 5 years ago.
When she started our treatment, she had been unable to walk for the previous two years and had to make use of a wheelchair during the day.
With the introduction of the Neurogenic diet, Sinemet was discontinued and replaced by our extracts. This approach allowed her to obtain improvements in her mobility and the side effects, she had been suffering, gradually disappeared. With the help of the extracts, she was able to perform essential movements without having any form of dyskinesia, freezing episodes and “off periods”.
However, our treatment could not enhance a proper Neurogenic activity, mainly because, being almost all day in a wheelchair, she had not been able to perform any form of exercise or any major muscular activity; these are essential factors needed to activate the processes of neurogenesis.
It is important to note that what occurred with this patient, is the opposite of what happened with the first patient, the 89 year old lady who has been able to take one hour walks every day. In relation to this, she made the following comment in her homemade video: “If you don’t walk at all, then you can’t walk.”
This personal observation represents her feelings after realizing that the more she can walk and exercise, the better her mobility. Whenever she stops walking, she realizes that it becomes harder to start again.
The experiences of these two patients, confirmed to us, that exercise and physical activity are the two main factors required for Neurogenic processes to take place. The use of our dietary intervention and extracts can only enhance the process of neurogenesis when the patient is able to perform a certain amount of exercise and physical activity.
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ASSESSMENT OF NEUROGENIC ACTIVITY
To assess the degrees of neuronal activity which can be induced through a specific type of intervention, the following suggestions are indicated for Parkinson’s disease and MSA patients:
1. –The assessment must be done in the morning. Patients must be free of Parkinson’s Disease medication and of any medicinal extract for at least 18 to 24 hours.
2. - To determine the degree of advancement of the disease, find out which movements or activities are the most difficult to perform, before taking the early morning extract or the prescribed PD drugs.
3. - The ability to perform each task needs to be evaluated. This examination measures, for example, the ability to stand up from a chair, getting out of bed, walking, opening doors, dressing, writing, taking a bath, etc.
4. - DNA repair and neuronal regeneration are slow processes therefore, to be able to observe any external changes, the evaluation tests are usually performed at 3 monthly intervals.
5. - The ability to improve performance in any of the above activities will indicate to us the degree in which the Neurogenic intervention has succeeded.
6. - Most neurological examinations and disability scales are designed to test the ability of a drug to improve mobility for a limited number of hours, following the taking of a specific drug. Here, instead, we test the ability of a treatment to regenerate neurons. Therefore, tests need to be taken at a time when no drugs or extracts had been used, whatsoever, for at least 18 hours.
7. – An improvement in the performance of any of the above activities will indicate to us that an enrichment in brain transmitter biosynthesis has occurred during sleeping hours. This endogenous enhancement of neurotransmitter biosynthesis can only occur as a result of an increase in the number of active brain dopaminergic neurons.
The following two patients shown in this documentary, started on our Neurogenic programme during 1998. A few months later, both patients decided to explore other alternatives to treat their disease.
5. - PARKINSON’S DISEASE
Video Filmed in July 2002
Patient’s Privacy ID Code: JN-1998
The first patient was offered a treatment called Deep Brain Stimulation (DBS). A few months later a deep brain stimulator was implanted in the ventralis intermedius nucleus of the thalamus.
The goal of DBS is to reduce the activity of overactive brain structures. High-Frequency Electrostimulation inhibits neuronal firing either by depolarization or by facilitating the action of inhibitory interneurons.
The effects of DBS are limited to tremor control and drug related dyskinesia. Patients with progressive Parkinson’s disease may eventually become disabled by akinesia and impairment of postural reflexes, requiring more aggressive pharmacotherapy or additional surgery.
To find out the long term response to DBS on this patient, we contacted him again in July 2002. He told us that initially, he had a good response to DBS, that lasted for over a year. Gradually, he had to go on increasing the dosages of Sinemet to 8, 10 and 12 times a day. He requested to us, that he would like to go back to using our extracts, to allow a reduction in Sinemet, because it was causing him adverse reactions. We sent him our extract RG-40 and he made a home-video for us, showing how he responded to our extract now, 4 years after a deep brain stimulator had been implanted.
We concluded from this experience, as well as from various other similar cases, that patients undergoing Deep Brain Stimulation will not be able to induce neurogenesis or neuronal reactivation in a significant way.
Our dietary intervention programme and extracts can only help patients using a Deep Brian Stimulator in a palliative manner, mainly to reduce adverse reactions, appearing after larger dosages of drugs have to be gradually reinstated.
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6. -PARKINSON’S DISEASE PATIENT
Video Filmed in March 2002
Patient’s Privacy ID Code: JE-1998
The following patient presented in this video, used our extracts on 1998, also just for a few months. After having a good response with them, he decided to try to explore a number of alternatives that he thought might help him in a similar way.
We contacted him again, 4 years later; in July 2002 to ask him to make a video for us showing whether there had been improvements in his ability to perform movements.
Unfortunately, he told us, he was not doing well.
In addition to the various dietary supplements he had been taking over the years, he had now to use Sinemet more than 14 times a day. This had caused him chronic constipation, with severe intestinal irritation. This irritation, caused mainly because by the dryness of the intestinal lining, had led to a shrinkage and damaging of his own intestinal flora. As a result, infections in this area became very frequent. Strong antibiotics had to be prescribed continuously.
Antibiotics exacerbated the dryness in the intestinal lining making the absorption of parkinsonian drugs like Sinemet even harder. He had to take higher doses of this drug, every time he had to use antibiotics.
Sinemet needed to be taken 20 or more times a day, just to allow him to perform essential movements. His condition had been worsening month after month, with the reappearance of many intolerable side effects.
The present condition of these two patients, contrasts dramatically with that of two of our patients who faithfully followed the Neurogenic diet, for the same four consecutive years, during which, the other two patients had taken alternative routes.
Please select to view the subject of your interest:
2b. RG-40 Organic Vegetable Extract
Protocol for studies on MSA and Parkinson’s Disease.
2c. The Neurogenic Diet in the Treatment of Neuro-degenerative Disorders
Basic proposal for clinical studies concerning MSA and Parkinson’s Disease.
Research Abstracts & Publications
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“There is a grandeur in this view of life, with its several powers, having being originally breathed by the Creator into a few forms or into one;”
Charles Darwin
”THE ORIGIN OF THE SPECIES”.
(Page 403, Chapter 15, Conclusion.)
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